Biochemistry and Molecular Biology

All Majors & Minors

Courses

  • BCMB-202.  Foundations in Biochemistry and Molecular Biology  

    Discussion of milestones and current topics in biochemistry and molecular biology. Students will be introduced to key BCMB skills and resources.  Co- or Prerequisites: BIO-201W, CHEM-205/205L and CHEM-206/206L (or CHEM-151/151L), a declared BCMB major, and sophomore status. One hour per week. One semester hour.

    BCMB-291.  Introduction to Research  

    Laboratory and library work, under the direction of a faculty member, designed to introduce the student to fundamental research procedures and data interpretation in the context of a research project. Upon completion of the work, a formal presentation must be given. This course may be taken more than once. At the time of registration, written consent of the instructor is required. Three hours of laboratory per week. Graded S/U. One semester hour.

    BCMB-307.  Biophysical Chemistry  

    An in-depth study of the theory and applications of chemical and physical equilibria in cells, enzyme kinetics, and thermodynamics of biochemical processes. Examples of such applications may include the study of the thermodynamics of metabolism, biological redox reactions, double strand formation in nucleic acids, equilibrium and energetics of protein denaturation, membrane potential, potassium ion channels, ligand binding, buffers, and osmosis and dialysis. Prerequisites: BIO-102W; CHEM-151 or 206; MATH-112; PHYS-111Q or 121Q. Three hours per week. Three semester hours. (LS if taken with CHEM-309a.)

    Note: Students may not receive credit for both BCMB-307 and CHEM-309.

    BCMB-350.  Selected Topics in Biochemistry and Molecular Biology 

    A course offered periodically in an area of special interest to students by a faculty member or a visiting lecturer. Prerequisite: permission of the instructor. Three hours per week, plus either intensive writing or three hours of laboratory, depending on the topic. Four semester hours. (LS, if lab associated with course.)

    BCMB-351.  Biochemistry I: Protein Biochemistry 

    The study of properties, structure, function and role(s) in life processes of proteins. Enzymatic mechanisms, kinetics, and the biochemical basis of selected physiological processes are also included. The laboratory introduces the theory and methods of protein isolation and analysis, including chromatography, electrophoresis, and enzyme kinetics. Prerequisites: BIO-201W; CHEM-205, 205L, 206 and 206L (or 151 and 151L); or permission of instructor. Three hours of lecture; three hours of laboratory. Four semester hours. (LS.)

    Students who have received credit for CHEM-347 may not enroll in BCMB-351.

    BCMB-380. Off-Campus Research 

    An approved, off-campus laboratory research experience supervised by an on-site adviser and faculty liaison involving a minimum of 120 hours of work. Before beginning the project, the student must submit a proposal to be approved by both the BCMB faculty and the on-site adviser. Upon completion of the work, written and oral reports must be presented to the department. Prerequisites: BIO-201L; CHEM-205L and either 151LQ or 206L. Graded S/U. Three semester hours. (I.)

    BCMB-381.  Internship 

    An off-campus academic/work experience with a primary focus on a laboratory research project. Before beginning the internship, the student must submit a proposal to be approved by the faculty internship advisor. Upon completion of the work, written and oral presentations must be made to the program faculty. Open to juniors and seniors. The term during which the internship work is performed will be noted by one of the following letters, to be added immediately after the internship course number: A (fall), B (winter), C (spring), or D (summer). Internships undertaken abroad will be so indicated by the letter I. The intern must complete a minimum of 120 hours of work. Prerequisites: BIO-201W and CHEM-206L. Graded S/U. Three semester hours. (I.)

    BCMB-382.  Internship  

    An off-campus academic/work experience with a primary focus on a laboratory research project. Before beginning the internship, the student must submit a proposal to be approved by the faculty internship advisor. Upon completion of the work, written and oral presentations must be made to the program faculty. Open to rising juniors and seniors. The term during which the internship work is performed will be noted by one of the following letters, to be added immediately after the internship course number: A (fall), B (winter), C (spring), or D (summer). Internships undertaken abroad will be so indicated by the letter I. The intern must complete a minimum of 160 hours of work. Prerequisites: BIO-201W and CHEM-206L. Graded S/U. Four semester hours. (I.)

    BCMB-391.  Research/Focused Inquiry  

    Laboratory and library work, under the direction of a faculty member, designed to introduce the student to fundamental research procedures and data interpretation in the context of a research project. Upon completion of the work, a formal presentation must be given. This course may be taken more than once. At the time of registration, written consent of the instructor is required. Six hours of laboratory per week. Graded S/U. Two semester hours.

    BCMB/BIO-426W.  Molecular Biology  

    A survey of gene structure, transcription, translation, regulation, and replication, as well as the theory underlying laboratory techniques used in their study. Laboratory experiments will include DNA and protein isolation, enzymatic manipulations, electrophoresis, and nucleic acid hybridization in an attempt to clone and analyze a bacterial gene. Prerequisites: BIO-201W; or permission of the instructor. Three hours of lecture; three hours of laboratory. Four semester hours. (LS.)

    BCMB/BIO-429W.  Structural Biology  

    An introduction to the principles of protein and DNA structure, X-ray crystallography, structure visualization and interpretation, and bioinformatics. The use of these concepts to understand biological function at the level of individual molecular interactions and at the level of complex processes will be demonstrated through specific biological examples. Laboratory work will emphasize structure-determining techniques and use of scientific databases and protein visualization software. Prerequisite: BIO-201W; or permission of the instructor. Three hours of lecture; three hours of laboratory per week. Four semester hours. (LS)

    BCMB/BIO/NEUR-433W.  Molecular Neurobiology 

    A study of the cellular and molecular basis of neuronal function. The course includes molecular properties of neurons, release of neurotransmitters, receptors in synaptic transmission, effects of drugs, synaptic plasticity, and neurological disorders. Prerequisites: BIO-201W; or permission of the instructor. Three hours of lecture; three hours of laboratory per week. Four semester hours. (LS.)

    BCMB-452W.  Biochemistry II: Metabolism  

    The study of diverse, complex interactions among biomolecules.  A comprehensive survey of metabolism including the cellular mechanisms underlying metabolic regulation.  The laboratory introduces advanced biochemical methods. This course (together with BCMB-426W, 429W or 433W) fulfills the capstone, oral and writing requirements of the major.  Prerequisite:  BCMB-351.  Three hours of lecture; three hours of laboratory. Four semester hours. (LS.)

    Note: Students who have received credit for CHEM-347 may not enroll in BCMB-452W.

    BCMB-480. Off-Campus Research

    An approved, off-campus laboratory research experience supervised by an on-site adviser and faculty liaison involving a minimum of 160 hours of work. Before beginning the project, the student must submit a proposal to be approved by both the BCMB faculty and the on-site adviser. Upon completion of the work, written and oral reports must be presented to the department. Prerequisites: BIO-201L; CHEM-205L and either 151LQ or 206L. Graded S/U. Four semester hours. (I.)

    BCMB-491.  Independent Research  

    Independent laboratory and library investigation in biochemistry and/or molecular biology, with oral progress reports and a research paper presented to the faculty research mentor. This course may be taken more than once. At the time of registration, written consent of the research advisor is required. 12—14 hours of laboratory per week. Four semester hours. (I.)

    BCMB-492W.  Independent Research 

    A continuation of BCMB-491 with an oral presentation to the BCMB faculty and a thesis or paper describing research work. Emphasis is placed on oral and written presentation, as well as advanced laboratory techniques. Prerequisites: BCMB-491, BCMB-452W (or concurrently). 12—14 hours of laboratory per week. Four semester hours. (I.)

    BCMB-493.  Molecular Biology Research 

    A course taken by a student who wishes to fulfill the molecular biology laboratory major requirement in a research setting. Work is done within a BCMB-391, BCMB-491, BCMB-492W or Summer Fellows research project. Beyond fulfilling the requirements of the research course, the student must demonstrate an understanding and facility with multiple techniques commonly used in the molecular biology laboratory. A student enrolls in this course the semester after successfully completing the requirements. Graded S/U. Prerequisite: Permission of research advisor and BCMB coordinators. Zero semester hours.

    *Note: Students must complete the associated research component (BCMB-391, BCMB-491, BCMB492W) prior to their last semester.