The HaMM Lab

The HaMM Laboratory provides opportunities for students interested in pursuing research on metabolic adaptations that occur in both cardiac and skeletal muscle. 

Dr. Kolwicz has a long-standing interest in the role of lipid metabolism in the development of cardiac dysfunction.  His past work, using genetic approaches, revealed a potential of enhanced cardiac lipid metabolism to protect the heart from acute and chronic stressors.  Current and future work will investigate the metabolic adaptations that occur in both cardiac and skeletal muscle during acute and chronic exercise training.  

The Heart and Muscle Metabolism Laboratory is located in IDC 216.The Heart and Muscle Metabolism Laboratory is located in IDC 216.

Recent Student Projects

  • Lola Holcomb: “The effects of short term fasting on endurance exercise capacity in male and female mice”
  • Lola Holcomb, Caitlin O’Neill, Elizabeth DeWitt: “The effect of ketogenic diet on endurance exercise capacity in mice.”
  • Elizabeth DeWitt, Ian Dysinger, Zachary Larmer: “High saturated and unsaturated fat diets yield different disease phenotypes in mice.”
  • Patrick Rowe, Caitlin O’Neill, Elizabeth DeWitt: “Endurance exercise capacity and substrate metabolism in male and female mice.”
  • Zachary Larmer, Elizabeth Dewitt: “The effects of ketogenic diet on metabolic parameters in obese mice.”

Innovation and Discovery Center

The HaMM Lab is located in the
Innovative Discovery Center, IDC#216.

 

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