The HaMM Lab
The HaMM Laboratory provides opportunities for students interested in pursuing research on metabolic adaptations that occur in both cardiac and skeletal muscle.
The Heart and Muscle Metabolism (HaMM) research laboratory in the Health and Exercise Physiology Department at Ursinus College is interested in understanding the precise metabolic adaptations that occur in cardiac and skeletal muscle during both health and disease states. One major focus is uncovering the role that changes in lipid metabolism play in the development of both cardiac and skeletal muscle dysfunction. These research projects utilize mouse models of high-fat feeding, including ketogenic diet, to identify changes in the structure and function of various organs. Another focus is identifying the metabolic changes that result from acute and chronic exercise training. In these projects mouse models of exercise training, including treadmill or voluntary wheel running, are used to investigate changes in various metabolic pathways.
Metabolism
HaMM lab bench space with up to 7 large workstations.
Shared lab space featuring spectrophotometer, lab shaker, and centrifuge
Langendorff isolated heart perfusion system used for assessing cardiac physiology.
Oxygraph system used for measuring oxygen consumption in isolated mitochondria
A centrifuge tube with mitochondria isolated from mouse hearts. The “powerhouse of the cell” is in the tube!
The Heart and Muscle Metabolism Laboratory is located in IDC 216.
Recent Student Projects |
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