The HaMM Lab
The HaMM Laboratory provides opportunities for students interested in pursuing research on metabolic adaptations that occur in both cardiac and skeletal muscle.
Dr. Kolwicz has a long-standing interest in the role of lipid metabolism in the development of cardiac dysfunction. His past work, using genetic approaches, revealed a potential of enhanced cardiac lipid metabolism to protect the heart from acute and chronic stressors. Current and future work will investigate the metabolic adaptations that occur in both cardiac and skeletal muscle during acute and chronic exercise training.
HaMM lab bench space with up to 7 large workstations.
Shared lab space featuring spectrophotometer, lab shaker, and centrifuge
Langendorff isolated heart perfusion system used for assessing cardiac physiology.
Oxygraph system used for measuring oxygen consumption in isolated mitochondria
A centrifuge tube with mitochondria isolated from mouse hearts. The “powerhouse of the cell” is in the tube!
Recent Student Projects