Biology

Rebecca Kohn

Rebecca Kohn earned her bachelor’s degree in Biochemistry at Dartmouth College and her Ph.D. in Biology at The Johns Hopkins University. She was a postdoctoral fellow at The Oklahoma Medical Research Foundation where she developed a research program examining nervous system function in the model organism Caenorhabditis elegans. Research projects in her laboratory are extended into the laboratory exercises in some of the courses she teaches.

In her research laboratory, undergraduate students explore questions pertaining to the function of the nervous system in the small worm Caenorhabditis elegans. Specifically, students work toward understanding how neurons regulate the release of neurotransmitters into synapses and how neurons protect themselves from damage due to oxidative stress. Student researchers examine genes important for nervous system activity. They also study how individual neurons in strains of worms with different levels of neuronal function respond to reactive oxidative species in the environment. Students present their findings at local and regional scientific conferences and are included as co-authors on peer-reviewed publications.

Title

Professor of Biology
Associate Dean of the College

Department

Biology

Degrees

  • A.B., Dartmouth College
  • Ph.D., Johns Hopkins University

Teaching

Common Intellectual Experience 

Genetics

Within the Cell: Further Explorations in Cell Biology and Genetics

Molecular Neurobiology

Research Interests

Regulation of neurotransmitter release

Neuroprotection

Recent Work

(*indicates undergraduate co-author)

*Chatburn, E., *Davis, N., *Duffy, B., *Fennelly, E., Minniti, A.N., Inestrosa, N.C., and Kohn, R.E. (2012). Glutamate receptors may not protect against oxidative stress in C. elegans. Impulse: The Premier Journal for Undergraduate Publications in Neuroscience, 1-5. 

*Porcelan, J., *Schindewolf, E., *Storey, K., *King, K., Hart, K., and Kohn, R.E. (2012). The effect of Vitamin E on the survival rate of unc-13 Caenorhabditis elegans mutants under oxidative stress. Impulse: The Premier Journal for Undergraduate Publications in Neuroscience, 1-8.  

Inestrosa, N., Rebolledo, D., Aldunate, R., Kohn, R., and Minniti, A. (2011). Copper ameliorates neuromuscular signaling defects in a C. elegans model of IBM through the reduction of A oligomeric species.  Journal of Neuroscience 31:10149-10158.

Jones, L.S., Allen, L., Cronise, K., Juneja, N., Kohn, R., *McClellan, K., Miller, A., *Nazir, A., Patel, A., Sweitzer, S.M., Vickery, E., Walton, A., and *Young, R. (2011). Using IMPULSE in and undergraduate course: a case study. The Journal of Undergraduate Neuroscience Education 9

*Kaas, B., *Vaidya, A.R., *Leatherman, A., *Schleidt, S., and Kohn, R.E. (2010). Technical Report: Exploring the basis of congenital myasthenic syndromes in an undergraduate course, using the model organism Caenorhabditis elegans. Invertebrate Neuroscience 10, 17-23.  

*Bleaken, B., *Zhou, J., *Myers, L., *Turner, N., and Kohn, R.E. (2010). Combined effect of ethanol and acetaminophen on the central nervous system of Daphnia magna. Impulse: The Premier Journal for Undergraduate Publications in Neuroscience, 1-6.  

*Kaas, B., *Krishnarao, K., *Marion, E., *Stuckey, L., and Kohn, R.E. (2009). Effects of melatonin and ethanol on the heart rate of Daphnia magna. Impulse: The Premier Journal for Undergraduate Publications in Neuroscience, 1-8.

*Leatherman, A.K., *Pirlamarla, B.P., *Rogman, S., *Yodice, D.S., and Kohn, R.E. (2009). The Neurophysiological effects of guarana and ethanol intake on Daphnia magna. Impulse: The Premier Journal for Undergraduate Publications in Neuroscience, 1-8.  

*Schleidt, S., *Indelicato, D., *Feigenbutz, A., *Lewis, C., and Kohn, R.E. (2009). Effect of an aspartame-ethanol mixture on Daphnia magna cardiac activity. Impulse: The Premier Journal for Undergraduate Publications in Neuroscience, 1-9.

*Vaidya, A., *Gurenlian, L., *Brady, L., *Romero, N.E., and Kohn, R.E. (2009). Cardioactive effects of diphenhydramine and curcumin on Daphnia magna. Impulse: The Premier Journal for Undergraduate Publications in Neuroscience, 1-12.  

*Rebolledo , D. L., Minniti , A. N., Grez, P.M., Fadic, R., Kohn, R., and Inestrosa, N.C. (2008). Inclusion Body Myositis, a View from the Caenorhabditis elegans Muscle. Molecular Neurobiology 38, 178-198.

Chapin, A., *P. Correa, *M. Maguire, R.E. Kohn. (2007). Synaptic Neurotransmission Protein UNC-13 Affects RNA Interference in Neurons. Biochem Biophys Res Comm 354: 1040-1044.

*Polinsky, C., *C. Houston, *J. Vado, *A. Shaikh, R.E. Kohn. (2006). Synaptic protein UNC-13 interacts with an F-box protein that may target it for degradation by proteasomes. Acta Biochim Pol 53: 145-8.