• Photo of Rebecca Lyczak

Rebecca Lyczak

In my research lab, we are interested in understanding what genes control early embryonic development. We use a combination of genetic approaches with time-lapse imaging of early cell divisions to uncover the role for different genes during development.

Rebecca Lyczak earned her Ph.D in Cell and Developmental Biology from Cornell Medical College and her B.S. in Biology and Education from The College of New Jersey.

Members of the Lyczak laboratory study a fundamental question of developmental biology - how does a single cell develop into a complex organism? Using C. elegans as a model, she uses genetic techniques to study the proteins involved in establishment of the anterior-posterior body axis in the one-cell embryo. Her work has been funded by grants from the National Institutes of Health and the National Science Foundation.




  • B.S. College of New Jersey
  • Ph.D., Cornell University


Molecular Genetics
Developmental Biology
Common Intellectual Experience

Research Interests

Role of the centrosome in polarity establishment
Role of the PAM-1 aminopeptidase in development
Mapping and identification of pam-1 suppressors

Recent Work

Saturno, D. M.*, Castanzo, D. T.*, Williams, M.*, Parikh, D. A.*, Jaeger, E., and Lyczak, R. (2017) Sustained centrosome-cortical contact ensures robust polarization of the one-cell C. elegans embryo. Developmental Biology 422,135-145.

Fortin, S.M., Marshall, S.L., Jaeger, E.C., Greene, P.E., Brady, L.K., Isaac, R.E., Schrandt, J.E., Brooks, D.R., and Lyczak R. (2010) The PAM-1 aminopeptidase regulates centrosome positioning to ensure anterior-posterior axis specification in one-cell C. elegans embryos. Developmental Biology 344, 992-1000.

Lyczak R., Zweier, L., Group, T., Murrow, M.A., Snyder, C., Kulovitz, L., Beatty, A., Smith, K., Bowerman, B. (2006)The puromycin-sensitive aminopeptidase PAM-1 is required for meiotic exit and anteroposterior polarity in the one-cell Caenorhabditis elegans embryo. Development 133, 4281-4292.