Rebecca Lyczak earned her Ph.D in Cell and Developmental Biology from Cornell Medical College and her B.S. in Biology and Education from The College of New Jersey.
Members of the Lyczak laboratory study a fundamental question of developmental biology - how does a single cell develop into a complex organism? Using C. elegans as a model, she uses genetic techniques to study the proteins involved in establishment of the anterior-posterior body axis in the one-cell embryo. Her work has been funded by grants from the National Institutes of Health and the National Science Foundation.
- B.S. College of New Jersey
- Ph.D., Cornell University
Common Intellectual Experience
Role of the centrosome in polarity establishment
Role of the PAM-1 aminopeptidase in development
Mapping and identification of pam-1 suppressors
Saturno, D. M.*, Castanzo, D. T.*, Williams, M.*, Parikh, D. A.*, Jaeger, E., and Lyczak, R. (2017) Sustained centrosome-cortical contact ensures robust polarization of the one-cell C. elegans embryo. Developmental Biology 422,135-145.
Fortin, S.M., Marshall, S.L., Jaeger, E.C., Greene, P.E., Brady, L.K., Isaac, R.E., Schrandt, J.E., Brooks, D.R., and Lyczak R. (2010) The PAM-1 aminopeptidase regulates centrosome positioning to ensure anterior-posterior axis specification in one-cell C. elegans embryos. Developmental Biology 344, 992-1000.
Lyczak R., Zweier, L., Group, T., Murrow, M.A., Snyder, C., Kulovitz, L., Beatty, A., Smith, K., Bowerman, B. (2006)The puromycin-sensitive aminopeptidase PAM-1 is required for meiotic exit and anteroposterior polarity in the one-cell Caenorhabditis elegans embryo. Development 133, 4281-4292.